CD73 generates adenosine in MET-amplified EGFR-TKIresistant cells and is regulated by FRA1. official website and that any information you provide is encrypted Ai-biopharma - Ai powered drug discovery All fields are required. Glassdoor gives you an inside look at what it's like to work at AllianThera Biopharma, including salaries, reviews, office photos, and more. Existing Users Login Here Log Into My Account New Users Create an Account Your Information Your Company's Information Security Passwords must be between 6 and 25 characters. Vantage homepage Search articles Our latest articles February 10, 2023 AllianThera Biopharma is Drug Discovery in China that focus on Protein-Coupled Receptors business. Clin Transl Oncol. AllianThera Biopharma was founded in China. Allianthera Biopharma, of Suzhou, China, a newly established biopharma firm, and Insilico Medicine Ltd., a deep-learning drug discovery firm based in Hong Kong, said they are collaborating to discover and develop molecules for novel targets in cancer and autoimmune diseases. With several decades of combined experience and successful multi-billion dollar deals, we have honed our formula to unlock future value powered by deep sector and capital markets knowledge, Closing of 138 Million Initial Public Offering, Ordinary Shares and Warrants will Commence Separate Trading. Reach out to AllianThera Biopharma directly regarding career opportunities. In the recent past, Dr. Ding was Vice-President of Pfizer External Science & Innovation focusing on emerging sciences, promising products and innovative technologies in the Asia Pacific regions. Chills in the biopharma M&A market are frequently blamed on the FTC. The company's File Number is listed as 001497025. Epub 2012 Jul 25. AllianThera Biopharma Name: AllianThera Biopharma Industry: Pharma Location: Suzhou, Jiangsu, China Employees: 10-50 Description: About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease b. Mechanism of resistance to epidermal growth factor receptor-tyrosine kinase inhibitors and a potential treatment strategy. This site needs JavaScript to work properly. view more Credit: Insilico Medicine. Company. In this lecture, Dr. Levitt describes how the work he began over 50 years ago has been vastly improved and expanded through the massive increase in computer speed and incredible advances in machine learning. AllianThera Biopharma headquarter office and corporate office address is located in 4-B101-125, Creative Industry Park, No. Dr. Ding and Dr. Cote-Sierra, each has 20+ years of R&D experiences and leadership roles in major pharmas, were former colleagues at Pfizer. Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancers dependent on the epidermal growth factor receptor pathway. Osimertinib in untreated EGFR-mutated advanced non-small-cell lung cancer. The data displayed is available through open government websites and public online directory. Shi P, Oh YT, Zhang G, Yao W, Yue P, Li Y, Kanteti R, Riehm J, Salgia R, Owonikoko TK, Ramalingam SS, Chen M, Sun SY. They share a common passion in discovery and develop novel therapeutics for patients in need the most. Vice President of Digital Technology at the Indiana Biosciences Research Institute Publications 24 February, 2023 'It's perfect': World's first generative AI-designed COVID drug to start clinical trials 22 February, 2023 Accelerating Efficient Drug Discovery With the Power of AI 10 February, 2023 Vaccines and neurology up for discussion, CROI 2023 GSK and Gileads long-acting HIV battle intensifies, CROI 2023 progress on efforts to cure HIV, Spotlight Cystic fibrosis developers take a deep breath, US deal watchdog's bark could be worse than its bite, Novo sows the seeds for a new heart failure approach. Since 2014 Insilico Medicine is focusing on generative models, reinforcement learning (RL), and other modern machine learning techniques for the generation of new molecular structures with the specified parameters, generation of synthetic biological data, target identification, and prediction of clinical trials outcomes. Dr. Ding and Dr. Cote-Sierra together with Prof. Zhijie Liu, a well-known GPCR structural biologist at the ShanghaiTech University, co-founded ATB to combine deep disease biology and drug R&D know-how with breakthrough technologies to tackle difficult diseases with underline disorders in the immune system. Disclaimer: AAAS and EurekAlert! 6005 Hidden Valley Road Suite 110 Carlsbad, CA 92011 858-293-4900. Claim your Free Employer Profile. Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, announced a collaboration to discover and develop molecules for novel targets in cancer and Founded in 2020. AllianThera Biopharma | Evaluate Home Vantage Pharmaceutical Companies Allianthera Biopharma Sorry, we didn't find any related vantage articles. The site is secure. SUZHOU, China, March 25, 2021 /PRNewswire/ --Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, announced a collaboration to discover and develop molecules for novel targets in cancer and autoimmune diseases. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases SUZHOU, China, March 25, 2021 /PRNewswire/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of . We take on biologically-validated targets that have been previously elusive but that have the potential to transform medicine. 6005 Hidden Valley Road Suite 110 Carlsbad, CA 92011 858-293-4900. 2016 Dec;15(12):3040-3054. doi: 10.1158/1535-7163.MCT-16-0313. Show more Frequently Asked Questions Please visit the vantage homepage for our latest articles or search our articles via the buttons below. ATB is a newly established biotechnology company led by seasoned drug hunters, Dr. Yuan-Hua Ding (CEO) and Dr. Javier Cote-Sierra (CSO), with seed money from Bohe Angel Fund, Anlong Venture andKatai Capital. Co-Founder & CEO at ATB (AllianThera Biopharma) Southborough, Massachusetts, United States 3K followers 500+ connections Join to view profile ATB (AllianThera Biopharma) University of. Accessibility Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Allianthera, Astrazeneca, Biontech, Immunoprecise, Isotopia, Istari, Kyowa Kirin, Lassen, Medicenna, Molecular Targeting, Nektar, Pfizer, Pieris, RDIF, Redhill, Seagen, Twist. AllianThera Biopharma Overview Work Here? A, Tumor volume of HCC827GR6 cells with, MeSH Senior Scientist 5 jobs; AllianThera Biopharma Locations. Our Pharma.AI platform has the potential to rapidly bring novel breakthrough medicines to patients . AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune . FDA panels loom for GSK and Biogen, with approval decisions due for Acadia and Biomarin. R01 CA190394/CA/NCI NIH HHS/United States, NCI CPTC Antibody Characterization Program, Kwon J, Bakhoum SF. Cookies are used to offer you a better browsing experience and to analyze our traffic. Website http://insilico.com/. About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge and 1F C1, No. The next couple of years should show whether inhaled genetic projects have potential. Yamaoka T, Ohmori T, Ohba M, Arata S, Kishino Y, Murata Y, Kusumoto S, Ishida H, Shirai T, Hirose T, Ohnishi T, Sasaki Y. Mol Cancer Ther. -, Le X, Puri S, Negrao MV, Nilsson MB, Robichaux J, Boyle T, et al. GSK shows that Cabenuva every two months is as good as daily Biktarvy, but Gilead looks to go even longer. By using this site, you agree that we may store and access cookies on your device. The company focuses on discovery and development of translational medicine in metabolic and immune-related diseases. 11 Allianthera Biopharma, Natick, MA, United States. A, PEM treatment co-opts cGAS-STING signaling, PEM treatment co-opts cGAS-STING signaling in MET-amplified EGFR-TKIresistant cells. Recently, Insilico Medicine secured $37 million in series B funding. Significance: 2023 SignalHire.com is operated by SENDERSYSTEMS LIMITED, AllianThera Biopharma headquarters is in Suzhou, Jiangsu. Please enable it to take advantage of the complete set of features! Linkedin The primary function of the role is to perform in vivo experiments to test pharmacodynamic effects of novel small molecules and to characterize them in models Posted 30+ days ago View all 2 available locations Senior Clinical Research Coordinator Northwell Health 3.9 Manhasset, NY 11030 $70,000 - $79,300 a year Full-time Monday to Friday + 1 are not responsible for the accuracy of news releases posted to EurekAlert! Linkedin. These data reveal that combined PEM and CD73 inhibition can co-opt tumor cell STING induction in TKI-resistant EGFR-mutated lung cancers and promote immunogenicity. Suzhou, Jiangsu BioPharma Companies are Investing $3 Billion in our Region Find Out Why Biopharma manufacturers have been thriving here for decades and recent growth confirms what we've known for many years this is a great place for business! 2023 PitchBook. Suzhou Tianma Group Tianji Bio-Pharmaceutical Company. Investors & Media. Allianthera Boston, Inc. is a Massachusetts Domestic Profit Corporation filed on March 25, 2021. AllianThera Biopharma 5 jobs. Immunotherapy has shown limited efficacy in patients with EGFR-mutated lung cancer. AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, have announced a collaboration to discover and develop molecules for novel targets in cancer and autoimmune diseases. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. image: AllianThera Biopharma collaborates on AI with Insilico Medicine. by contributing institutions or for the use of any information through the EurekAlert system. and transmitted securely. Design Therapeutics. Cancer Discov 2020;10:2639. * We use standard office opening hours in near AllianThera Biopharma's location as default value for unknown and outdated data. Now, says Dr. Levitt, Insilico Medicine is using AI to create an entirely new AI-driven drug discovery pipeline from A to Z. "Most of the pharmaceutical and biotechnology companies these days are working more or less on similar well-known targets and the innovation is in new molecular structures. Integrated, Universal & Experimentally-Validated, Our mission is to accelerate drug discovery and drug development. In 2023, AllianThera Biopharma is currently focus on Protein-Coupled Receptors sector. -, DaSilva JO, Yang K, Surriga O, Nittoli T, Kunz A, Franklin MC, et al. Terms were not disclosed. An official website of the United States government. PMC AllianThera Biopharma, Boston, MA, United States Fiona Elwood Department of Neuroscience, Novartis Institutes for BioMedical Research (NIBR), Cambridge, MA, United States Seemin S. Ahmed Here, we discover that MET amplification, the most common mechanism of resistance to third-generation EGFR tyrosine kinase inhibitors (TKI), activates tumor cell STING, an emerging determinant of cancer immunogenicity (1). CD73 coactivation with STING in MET-driven EGFR-TKIresistant cells. N Engl J Med 2018;378:11325. A readout in the next few weeks could put pemvidutide on course for blockbuster sales or not. At ATB we would like to focus on disease biology and to adapt different technologies to tackle mix of new targets and some completely radical targets that even big pharmaceutical companies consider too risky to explore. They cover business area such as developer, GPCR-target drug, biological target, artificial intelligence technology, (GPCR. SUZHOU, China, March 25, 2021 /PRNewswire/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and . 2016 Oct 1;380(2):494-504. doi: 10.1016/j.canlet.2016.07.021. 700, Boston, MA 02110. What you see here scratches the surface Request a free trial Insilico Medicine sends first generative AI-designed drug for COVID-19 and variants to clinic, Tech journalist and filmmaker Amelia Martyn-Hemphill announced as Docuthon judge, Emmy Award-winning filmmaker Oren Rosenfeld joins Insilico Medicine's Docuthon as judge, Insilico Medicine receives FDA Orphan Drug Designation for generative AI discovered and designed drug for idiopathic pulmonary fibrosis, New paper explores Insilico Medicine's generative AI drug design platform Chemistry42, Insilico Medicine opens largest AI-powered biotechnology research center in the Middle East, New study uses AlphaFold and AI to accelerate design of novel drug for liver cancer, Insilico Medicine announces positive topline results of the New Zealand Phase 1 trial of INS018_055, an AI-designed drug for an AI-discovered target, Insilico Medicine nominates potential first-in-class preclinical candidate with novel AI-designed structure for novel AI-discovered target in immuno-oncology, Insilico Medicine Awarded Over $700,000 to Design New Contraceptive Options with AI, Insilico Medicine receives Company of the Year Award at BioCentury-BayHelix East-West Summit, Insilico Medicine Signs Strategic Research Collaboration with Sanofi worth up to $1.2 Billion, Deepfake Technology in Drug Design. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Go to your account and send up to 300 emails per day using the Free plan. AllianThera Biopharma. Cancer Lett. Co-Founder & CSO of Allianthera Biopharma and Former Head of Inflammation & Immunology External Innovation at Sanofi Genzyme Yuan-Hua Ding, PhD Advisor Co-Founder & CEO of Allianthera Biopharma and Co-CEO at the BayRay Innovation Center, former Head of Pfizer Asia Discovery Labs -. This is the AllianThera Biopharma company profile. -, Soria JC, Ohe Y, Vansteenkiste J, Reungwetwattana T, Chewaskulyong B, Lee KH, et al. Advanced Search Title. 2021325 () . All rights reserved. Eccogene is specialized in disease biology, medicinal chemistry, and . . AllianThera Biopharma lead by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases, image:AllianThera Biopharma collaborates on AI with Insilico Medicine. Altimmune aims to build Momentum in obesity, Go or no go? Since 2014 Insilico Medicine is focusing on generative models, reinforcement learning (RL), and other modern machine learning techniques for the generation of new molecular structures with the specified parameters, generation of synthetic biological data, target identification, and prediction of clinical trials outcomes. Changes wont be saved until you sign up for an Enhanced Profile subscription. Careers. Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep knowledge in Immunology and Oncology and drug discovery expertise with partners' technologies while leveragingunique strengths in different geographies, East or West. MET amplification upregulates CD73 to suppress tumor cell STING induction and T-cell responsiveness in TKI-resistant, EGFR-mutated lung cancer, identifying a strategy to enhance immunogenicity and improve treatment. . We are building a strong portfolio through internal R&D programs and external partnerships with an initial focus on unmet medical needs in immunology and cancer. Piper Companies is always on the lookout for new talent. We are looking for team players who collaborate, communicate and innovate. Clipboard, Search History, and several other advanced features are temporarily unavailable. We are very happy that he decided to form a company focused on leading-edge technologies with transformative potential, assembled a great team of seasoned drug hunters and chose to collaborate with us, on both target discovery and generative chemistry", said Alex Zhavoronkov, PhD, CEO of Insilico Medicine. Sorry, we didn't find any related vantage articles. 328 Xinghu Street Combined therapy with mutant-selective EGFR inhibitor and Met kinase inhibitor for overcoming erlotinib resistance in EGFR-mutant lung cancer. Cells 2018;7:212. Reports the latest medical biotech, pharma, clinical trials, FDA, mergers, acquisitions, funding and more. Founder, CEO & Director Co-Founder and CEO of Izana Bioscience & Akaza, Co-Founder of Pathios Therapeutics, Co-investor, Former MD in ECM at Socit Gnrale and ABN AMRO Rothschild, Founder of Cryfield Investments, Co-Founder of MoonLake Immunotherapeutics and Former Head of Global Business Unit Immunology, Hepatalogy and Dermatology at Novartis, Co-Founder & CSO of Allianthera Biopharma and Former Head of Inflammation & Immunology External Innovation at Sanofi Genzyme, Co-Founder & CEO of Allianthera Biopharma and Co-CEO at the BayRay Innovation Center, former Head of Pfizer Asia Discovery Labs, JATT Acquisition Corp. is made up of a team of global drug hunters, proven entrepreneurs, pharma veterans and financial operators. The companies utilized a pipeline of Insilico Medicine's artificial intelligence platforms including PandaOmics to identify a list of promising targets in cancer and autoimmune diseases and prioritize novel high-confidence targets to progress into early-stage drug discovery. FOIA 252021500ESTAllianThera BiopharmaATBInsilicoMedicine PandaOmicsInsilico Medicine He touches on OPUS-X and AlphaFold and how each contribution has advanced our capability and understanding. 328 Xinghu Street Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone Suzhou, Jiangsu China AllianThera Biopharma Timeline 2021 2022 Date Founded Financing Round Want detailed data on 3M+ companies? 9 Guanghua Road, Chaoyang District, Beijing. Get involved to accelerate your cross-border partnering strategies. Polly Firs The companies utilized a pipeline of Insilico Medicine's artificial intelligence platforms including PandaOmics to identify a list of promising targets in cancer and autoimmune diseases and prioritize novel high-confidence targets to progress into early-stage drug discovery. China, developerGPCR-target drugbiological targetartificial intelligence technology(GPCR. New preclinical data from Ascentage Pharma Group International, of Suzhou, China, demonstrated . This website expressly disclaims the accuracy, adequacy, or completeness of any data and shall not be liable for any errors, omissions or other defects in, delays or interruptions in such data, or for any actions taken in reliance thereon. The Registered Agent on file for this company is CT Corporation System and is located at 155 Federal St., Ste. "Most of the pharmaceutical and biotechnology companies these days are working more or less on similar well-known targets and the innovation is in new molecular structures. See this image and copyright information in PMC. We use cookies on this website. AllianThera Biopharma Overview Work Here? A, Venn diagram showing the, CD73 is regulated by oncogenic MET in lung cancer cells. Suzhou, Jiangsu 2021325AllianThera Biopharma Insilico MedicineInsilico MedicinePandaOmics . BioWorld Briefs Other news to note Coronavirus AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases SUZHOU, China, March 25, 2021 /PRNewswire/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of . At Recludix, we are innovators and inventors. AllianThera Biopharma is Drug Discovery in China that focus on Protein-Coupled Receptors business. Alpha Biopharma - Specialize in drug innovation from clinical development to commercialization success. Win whats next. Scientists use machine learning to predict major clinical forms of drug cardiotoxicity, Scientists Use Virtual Reality to Refine New AI-Generated Drugs for COVID-19, New artificial intelligence model to bridge biology and chemistry, Frost & Sullivan recognizes Insilico as innovation leader in drug discovery, Insilico and Astellas collaborate on AI for a conventionally challenging target family, Insilico collaborates with Boehringer Ingelheim on AI system for target discovery, Beijing Tide Pharmaceutical and Insilico Medicine enter into an agreement for cancer therapy, FierceMedTech names Insilico Medicine as one of its 'Fierce 15' companies of 2019, MIT Technology Review selects AI molecular design as a breakthrough and highlights Insilico, AI preclinical research program targeting brain cancers starts at Insilico Medicine, Insilico collaborates with Pfizer on novel data and AI system for target discovery, Insilico Medicine publishes molecular structures for the key protein target of 2019-nCoV, Beiersdorf and Insilico employ AI technology in computer-simulated skin research, Deep learning enables rapid identification of potent DDR1 kinase inhibitors, 'It's perfect': World's first generative AI-designed COVID drug to start clinical trials, Accelerating Efficient Drug Discovery With the Power of AI, Insilico Gains FDA's First Orphan Drug Designation for AI Candidate, Unit 310, 3/F, Building 8W, Phase 2, Hong Kong Science Park, Pak Shek Kok, New Territories, Hong Kong. , Chewaskulyong B, Lee KH, et al readout in the next few weeks put... 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Acquisitions, funding and more growth factor receptor-tyrosine kinase inhibitors in non-small-cell lung cancers dependent on the.... Value for unknown and outdated data are required you provide is encrypted Ai-biopharma - AI powered drug discovery from. 15 ( 12 ):3040-3054. doi: 10.1016/j.canlet.2016.07.021 a potential treatment strategy registered. 2023 AllianThera Biopharma Sorry, we did n't find any related vantage articles 5 jobs ; AllianThera Biopharma is! Limited, AllianThera Biopharma Locations inhibitors in non-small-cell lung cancers dependent on the epidermal growth factor kinase! Suite 110 Carlsbad, CA 92011 858-293-4900 agree that we may store access..., Puri s, Negrao MV, Nilsson MB, Robichaux J, Boyle T, al! Targetartificial intelligence technology, ( GPCR few weeks could put pemvidutide on course blockbuster!, Universal & Experimentally-Validated, our mission is to accelerate drug discovery and drug.. 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( HHS ) cover business area such as developer, GPCR-target drug, biological target, intelligence... R01 CA190394/CA/NCI NIH HHS/United States, NCI CPTC Antibody Characterization Program, Kwon,., Nittoli T, Chewaskulyong B, Lee KH, et al, Universal & Experimentally-Validated, our is. Piper Companies is always on the FTC cover business area such as developer, GPCR-target drug biological. Mechanism of resistance to epidermal growth factor receptor-tyrosine kinase inhibitors in non-small-cell lung dependent... In disease biology, medicinal chemistry, and several other advanced features temporarily. To epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancers and promote immunogenicity n't find any vantage!